New COVID Variant NB.1.8.1 Detected in U.S., Linked to Surge in China

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The Voice News :The CDC’s airport screening program has identified multiple cases of a new COVID-19 variant, NB.1.8.1, in international travelers arriving in the U.S. The variant, currently dominant in China, has been detected at airports in California, Washington, Virginia, and the New York City area, according to Ginkgo Bioworks’ sequencing data.

Sequencing records from April 22 to May 12 reveal that infected travelers came from countries including China, Taiwan, Japan, South Korea, Vietnam, France, Spain, the Netherlands, and Thailand. Additional domestic cases have been confirmed in Ohio, Rhode Island, and Hawaii, with initial cases in California and Washington traced back to March and early April.

The variant, a descendant of the XDV lineage, is driving a sharp increase in hospital visits in Hong Kong and rising cases in Taiwan. While no evidence suggests increased severity, authorities in Hong Kong have urged the public to wear masks in crowded areas and on public transit.

Preliminary research from China suggests NB.1.8.1 does not significantly evade immunity but binds more effectively to human cells, potentially increasing transmissibility.

During a recent FDA vaccine advisory meeting, experts discussed whether to update COVID-19 vaccines for the upcoming fall and winter. Pfizer and Moderna presented early data showing that a new vaccine targeting the LP.8.1 variant, another JN.1 descendant, could offer broader protection, including against NB.1.8.1. The panel agreed on targeting a JN.1 variant, though opinions varied on which specific strain.

Despite the unpredictable evolution of the virus, health officials noted the emergence of a seasonal pattern in the U.S., typically peaking in summer and winter. COVID-19 levels are currently low, based on ER visits and wastewater analysis.

“We’re seeing a more predictable seasonal trend after five years of tracking this virus,” said CDC’s Natalie Thornburg, citing ongoing research into COVID’s seasonality.

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